Holographic tomography (HT) is a label-free quantitative microscopic imaging method which uses digital holographic microscopy to record the complex information of a biological sample as digital holograms and then numerically reconstruct the sample’s refractive index (RI) distribution in 3D. The RI values are a key parameter for bio-examination at its native cell culture medium, which correlate with metabolic activities and spatiotemporal distribution of biophysical parameters of cells and their internal organelles, tissues, and small-scale biological objects. The insight on this rapidly growing HT field of research and its applications in biology will be briefly discussed. Followed by the summary of the HT principle and highlight recent technical advancement in HT and its applications.

Speaker Bio: Dr. Vinoth Balasubramani is currently a senior researcher at King Abdullah University of Science and Technology (KAUST), Saudi Arabia. Dr. Vinoth obtained his PhD degree from National Taiwan Normal University (NTNU), Taiwan. He is a recipient of the ‘National Taiwan scholarship’ from the Taiwan Ministry of Education-Taiwan. His PhD research solved several fundamental issues in holographic tomographic imaging and analysis of living cells. His PhD research output was honored with an ‘Outstanding graduate award - 2019’ from the Taiwan government. He was awarded with ‘Young Research Scholar Award - 2018’ from the ministry of Taiwan and China Technical Consultants Inc., (CTCI) which is the highest award for a PhD student in Taiwan. He is also honored with ‘NTNU Outstanding Studentship Award’. His current research is focused on the development of advanced 3D multimodal imaging systems for the biomedical applications. His research interests include Holographic Optical Elements, Wavefront Engineering, Adaptive optics, Holographic Tomography, Fiber and free-space optics etc.

Physicum seminars are meant for a broad auditorium of physicists and materials scientists, as well as for interested people from other natural and exact sciences (including bachelor level students) and aim at introducing what is important and new in a certain field, or where a specific research direction has reached today.